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Functional Interaction of Ca(V) Channel Isoforms with Ryanodine Receptors Studied in Dysgenic Myotubes

The L-type Ca(2+) channels Ca(V)1.1 (α(1S)) and Ca(V)1.2 (α(1C)) share properties of targeting but differ by their mode of coupling to ryanodine receptors in muscle cells. The brain isoform Ca(V)2.1 (α(1A)) lacks ryanodine receptor targeting. We studied these three isoforms in myotubes of the α(1S)-...

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Détails bibliographiques
Auteurs principaux: Schuhmeier, Ralph Peter, Gouadon, Elodie, Ursu, Daniel, Kasielke, Nicole, Flucher, Bernhard E., Grabner, Manfred, Melzer, Werner
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305232/
https://ncbi.nlm.nih.gov/pubmed/15626717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051318
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