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Self-Consistent Proteomic Field Theory of Stochastic Gene Switches

We present a self-consistent field approximation approach to the problem of the genetic switch composed of two mutually repressing/activating genes. The protein and DNA state dynamics are treated stochastically and on an equal footing. In this approach the mean influence of the proteomic cloud creat...

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Autors principals: Walczak, Aleksandra M., Sasai, Masaki, Wolynes, Peter G.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305159/
https://ncbi.nlm.nih.gov/pubmed/15542546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.050666
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