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Gene-Gene Cooperativity in Small Networks

We show how to construct a reduced description of interacting genes in noisy, small regulatory networks using coupled binary spin variables. Treating both the protein number and gene expression state variables stochastically and on equal footing, we propose a mapping that connects the molecular leve...

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Bibliografische gegevens
Hoofdauteurs: Walczak, Aleksandra M., Wolynes, Peter G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711489/
https://ncbi.nlm.nih.gov/pubmed/19486675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.005
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