Interpreting Second-Harmonic Generation Images of Collagen I Fibrils

Fibrillar collagen, being highly noncentrosymmetric, possesses a tremendous nonlinear susceptibility. As a result, second-harmonic generation (SHG) microscopy of collagen produces extremely bright and robust signals, providing an invaluable tool for imaging tissue structure with submicron resolution...

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Bibliografiske detaljer
Main Authors: Williams, Rebecca M., Zipfel, Warren R., Webb, Watt W.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Spectroscopy, Imaging, Other Techniques
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305140/
https://ncbi.nlm.nih.gov/pubmed/15533922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.047308
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