טוען...
Misfolding Pathways of the Prion Protein Probed by Molecular Dynamics Simulations
Although the cellular monomeric form of the benign prion protein is now well characterized, a model for the monomer of the misfolded conformation (PrP(Sc)) remains elusive. PrP(Sc) quickly aggregates into highly insoluble fibrils making experimental structural characterization very difficult. The te...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Biophysical Society
2005
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1305135/ https://ncbi.nlm.nih.gov/pubmed/15556981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.049882 |
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