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A Double-Deletion Method to Quantifying Incremental Binding Energies in Proteins from Experiment: Example of a Destabilizing Hydrogen Bonding Pair

The contribution of a specific hydrogen bond in apoflavodoxin to protein stability is investigated by combining theory, experiment and simulation. Although hydrogen bonds are major determinants of protein structure and function, their contribution to protein stability is still unclear and widely deb...

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Bibliografiska uppgifter
Huvudupphovsmän: Campos, Luis A., Cuesta-López, Santiago, López-Llano, Jon, Falo, Fernando, Sancho, Javier
Materialtyp: Artigo
Språk:Inglês
Publicerad: Biophysical Society 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305133/
https://ncbi.nlm.nih.gov/pubmed/15556980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.050203
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