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Effects of Kv1.2 Intracellular Regions on Activation of Kv2.1 Channels

Depolarizing voltage steps activate voltage-dependent K(+) (Kv) channels by moving the voltage sensor, which triggers a coupling reaction leading to the opening of the pore. We constructed chimeric channels in which intracellular regions of slowly activating Kv2.1 channels were replaced by respectiv...

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Bibliografiske detaljer
Main Authors: Scholle, Annette, Zimmer, Thomas, Koopmann, Rolf, Engeland, Birgit, Pongs, Olaf, Benndorf, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304496/
https://ncbi.nlm.nih.gov/pubmed/15298895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040550
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