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Hydration of Enzyme in Nonaqueous Media Is Consistent with Solvent Dependence of Its Activity

Water plays an important role in enzyme structure and function in aqueous media. That role becomes even more important when one focuses on enzymes in low water media. Here we present results from molecular dynamics simulations of surfactant-solubilized subtilisin BPN′ in three organic solvents (octa...

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Bibliografische gegevens
Hoofdauteurs: Yang, Lu, Dordick, Jonathan S., Garde, Shekhar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Biophysical Society 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304491/
https://ncbi.nlm.nih.gov/pubmed/15298890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.041269
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