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Osmolyte Trimethylamine-N-Oxide Does Not Affect the Strength of Hydrophobic Interactions: Origin of Osmolyte Compatibility

Osmolytes are small organic solutes accumulated at high concentrations by cells/tissues in response to osmotic stress. Osmolytes increase thermodynamic stability of folded proteins and provide protection against denaturing stresses. The mechanism of osmolyte compatibility and osmolyte-induced stabil...

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Autori principali: Athawale, Manoj V., Dordick, Jonathan S., Garde, Shekhar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366635/
https://ncbi.nlm.nih.gov/pubmed/15894642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056671
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