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Hydration of Enzyme in Nonaqueous Media Is Consistent with Solvent Dependence of Its Activity
Water plays an important role in enzyme structure and function in aqueous media. That role becomes even more important when one focuses on enzymes in low water media. Here we present results from molecular dynamics simulations of surfactant-solubilized subtilisin BPN′ in three organic solvents (octa...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biophysical Society
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304491/ https://ncbi.nlm.nih.gov/pubmed/15298890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.041269 |
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