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Folding λ-Repressor at Its Speed Limit
We show that the five-helix bundle λ(6–85) can be engineered and solvent-tuned to make the transition from activated two-state folding to downhill folding. The transition manifests itself as the appearance of additional dynamics faster than the activated kinetics, followed by the disappearance of th...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Biophysical Society
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304381/ https://ncbi.nlm.nih.gov/pubmed/15240492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.039040 |
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