Transfer of the Cholera Toxin A1 Polypeptide from the Endoplasmic Reticulum to the Cytosol Is a Rapid Process Facilitated by the Endoplasmic Reticulum-Associated Degradation Pathway

The active pool of internalized cholera toxin (CT) moves from the endosomes to the Golgi apparatus en route to the endoplasmic reticulum (ER). The catalytic CTA1 polypeptide is then translocated from the ER to the cytosol, possibly through the action of the ER-associated degradation (ERAD) pathway....

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Hlavní autoři: Teter, Ken, Allyn, Rebecca L., Jobling, Michael G., Holmes, Randall K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC130427/
https://ncbi.nlm.nih.gov/pubmed/12379694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6166-6171.2002
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