Staphylococcus aureus Aconitase Inactivation Unexpectedly Inhibits Post-Exponential-Phase Growth and Enhances Stationary-Phase Survival

Staphylococcus aureus preferentially catabolizes glucose, generating pyruvate, which is subsequently oxidized to acetate under aerobic growth conditions. Catabolite repression of the tricarboxylic acid (TCA) cycle results in the accumulation of acetate. TCA cycle derepression coincides with exit fro...

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Détails bibliographiques
Auteurs principaux: Somerville, Greg A., Chaussee, Michael S., Morgan, Carrie I., Fitzgerald, J. Ross, Dorward, David W., Reitzer, Lawrence J., Musser, James M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Bacterial Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC130419/
https://ncbi.nlm.nih.gov/pubmed/12379717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6373-6382.2002
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