Staphylococcus aureus Aconitase Inactivation Unexpectedly Inhibits Post-Exponential-Phase Growth and Enhances Stationary-Phase Survival

Staphylococcus aureus preferentially catabolizes glucose, generating pyruvate, which is subsequently oxidized to acetate under aerobic growth conditions. Catabolite repression of the tricarboxylic acid (TCA) cycle results in the accumulation of acetate. TCA cycle derepression coincides with exit fro...

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Detalhes bibliográficos
Main Authors: Somerville, Greg A., Chaussee, Michael S., Morgan, Carrie I., Fitzgerald, J. Ross, Dorward, David W., Reitzer, Lawrence J., Musser, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130419/
https://ncbi.nlm.nih.gov/pubmed/12379717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6373-6382.2002
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