Staphylococcus aureus Aconitase Inactivation Unexpectedly Inhibits Post-Exponential-Phase Growth and Enhances Stationary-Phase Survival

Staphylococcus aureus preferentially catabolizes glucose, generating pyruvate, which is subsequently oxidized to acetate under aerobic growth conditions. Catabolite repression of the tricarboxylic acid (TCA) cycle results in the accumulation of acetate. TCA cycle derepression coincides with exit fro...

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Main Authors: Somerville, Greg A., Chaussee, Michael S., Morgan, Carrie I., Fitzgerald, J. Ross, Dorward, David W., Reitzer, Lawrence J., Musser, James M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Bacterial Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC130419/
https://ncbi.nlm.nih.gov/pubmed/12379717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6373-6382.2002
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