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Electrostatic Sequestration of PIP(2) on Phospholipid Membranes by Basic/Aromatic Regions of Proteins
The basic effector domain of myristoylated alanine-rich C kinase substrate (MARCKS), a major protein kinase C substrate, binds electrostatically to acidic lipids on the inner leaflet of the plasma membrane; interaction with Ca(2+)/calmodulin or protein kinase C phosphorylation reverses this binding....
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304070/ https://ncbi.nlm.nih.gov/pubmed/15041659 |
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