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A Computational Model for the Electrostatic Sequestration of PI(4,5)P(2) by Membrane-Adsorbed Basic Peptides

The multivalent acidic phospholipid phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) plays a key role in many biological processes. Recent studies show that unstructured clusters of basic residues from a number of peripheral proteins can laterally sequester PI(4,5)P(2) in membranes. Specifically,...

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Detalhes bibliográficos
Main Authors: Wang, Jiyao, Gambhir, Alok, McLaughlin, Stuart, Murray, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304052/
https://ncbi.nlm.nih.gov/pubmed/15041641
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