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Adenylation-Dependent Conformation and Unfolding Pathways of the NAD(+)-Dependent DNA Ligase from the Thermophile Thermus scotoductus
In the last few years, an increased attention has been focused on NAD(+)-dependent DNA ligases. This is mostly due to their potential use as antibiotic targets, because effective inhibition of these essential enzymes would result in the death of the bacterium. However, development of an efficient dr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1303902/ https://ncbi.nlm.nih.gov/pubmed/14747344 |
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