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Adenylation-Dependent Conformation and Unfolding Pathways of the NAD(+)-Dependent DNA Ligase from the Thermophile Thermus scotoductus

In the last few years, an increased attention has been focused on NAD(+)-dependent DNA ligases. This is mostly due to their potential use as antibiotic targets, because effective inhibition of these essential enzymes would result in the death of the bacterium. However, development of an efficient dr...

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Bibliografische gegevens
Hoofdauteurs: Georlette, Daphné, Blaise, Vinciane, Bouillenne, Fabrice, Damien, Benjamin, Thorbjarnardóttir, Sigridur H., Depiereux, Eric, Gerday, Charles, Uversky, Vladimir N., Feller, Georges
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Biophysical Society 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303902/
https://ncbi.nlm.nih.gov/pubmed/14747344
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