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FRET Detection of Cellular α(4)-Integrin Conformational Activation

Integrins are cell adhesion receptors, expressed on every cell type, that have been postulated to undergo conformational changes upon activation. Here, different affinity states were generated by exposing α(4)-integrins to divalent ions or by inside-out activation using a chemokine receptor. We prob...

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Detalhes bibliográficos
Main Authors: Chigaev, Alexandre, Buranda, Tione, Dwyer, Denise C., Prossnitz, Eric R., Sklar, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303696/
https://ncbi.nlm.nih.gov/pubmed/14645084
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