FRET detection of lymphocyte function–associated antigen-1 conformational extension

Lymphocyte function–associated antigen 1 (LFA-1, CD11a/CD18, αLβ2-integrin) and its ligands are essential for adhesion between T-cells and antigen-presenting cells, formation of the immunological synapse, and other immune cell interactions. LFA-1 function is regulated through conformational changes...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Chigaev, Alexandre, Smagley, Yelena, Haynes, Mark K., Ursu, Oleg, Bologa, Cristian G., Halip, Liliana, Oprea, Tudor, Waller, Anna, Carter, Mark B., Zhang, Yinan, Wang, Wei, Buranda, Tione, Sklar, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279228/
https://ncbi.nlm.nih.gov/pubmed/25378583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1050
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