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Simulations of Oligomeric Intermediates in Prion Diseases
We extend our previous stochastic cellular automata-based model for two-dimensional (areal) aggregation of prion proteins on neuronal surfaces. The new anisotropic model allows us to simulate both strong β-sheet and weaker attachment bonds between proteins. Constraining binding directions allows us...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1303448/ https://ncbi.nlm.nih.gov/pubmed/14507687 |
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