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The Pathway of Oligomeric DNA Melting Investigated by Molecular Dynamics Simulations

Details of the reaction coordinate for DNA melting are fundamental to much of biology and biotechnology. Recently, it has been shown experimentally that there are at least three states involved. To clarify the reaction mechanism of the melting transition of DNA, we perform 100-ns molecular dynamics...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wong, Ka-Yiu, Pettitt, B. Montgomery
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599842/
https://ncbi.nlm.nih.gov/pubmed/18952784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.141010
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