Ca(2+) Regulation of Rabbit Skeletal Muscle Thin Filament Sliding: Role of Cross-Bridge Number

We investigated how strong cross-bridge number affects sliding speed of regulated Ca(2+)-activated, thin filaments. First, using in vitro motility assays, sliding speed decreased nonlinearly with reduced density of heavy meromyosin (HMM) for regulated (and unregulated) F-actin at maximal Ca(2+). Sec...

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Main Authors: Liang, Bo, Chen, Ying, Wang, Chien-Kao, Luo, Zhaoxiong, Regnier, Michael, Gordon, Albert M., Chase, P. Bryant
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2003
Assuntos:
Muscles and Contractility
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303351/
https://ncbi.nlm.nih.gov/pubmed/12944292
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