Functional and Biochemical Analysis of the Type 1 Inositol (1,4,5)-Trisphosphate Receptor Calcium Sensor

Modulation of the type 1 inositol (1,4,5)-trisphosphate receptors (InsP(3)R1) by cytosolic calcium (Ca(2+)) plays an essential role in their signaling function, but structural determinants and mechanisms responsible for the InsP(3)R1 regulation by Ca(2+) are poorly understood. Using DT40 cell expres...

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Detalhes bibliográficos
Main Authors: Tu, Huiping, Nosyreva, Elena, Miyakawa, Tomoya, Wang, Zhengnan, Mizushima, Akiko, Iino, Masamitsu, Bezprozvanny, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Channels, Receptors, and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303085/
https://ncbi.nlm.nih.gov/pubmed/12829484
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