The high-affinity calcium[bond]calmodulin-binding site does not play a role in the modulation of type 1 inositol 1,4,5-trisphosphate receptor function by calcium and calmodulin.

Modulation of the inositol 1,4,5-trisphosphate (InsP(3)) receptors (InsP(3)R) by cytosolic calcium (Ca(2+)) plays an essential role in Ca(2+) signalling, but structural determinants and mechanisms responsible for the InsP(3)R regulation by Ca(2+) are poorly understood. In the present study, we expre...

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Detalhes bibliográficos
Main Authors: Nosyreva, Elena, Miyakawa, Tomoya, Wang, Zhengnan, Glouchankova, Lyuba, Mizushima, Akiko, Iino, Masamitsu, Bezprozvanny, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222719/
https://ncbi.nlm.nih.gov/pubmed/11972451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011789
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