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Ion Channels of Alamethicin Dimer N-Terminally Linked by Disulfide Bond

A covalent dimer of alamethicin Rf30 was synthesized by linking the N-termini by a disulfide bond. When the dimer peptides were added to the cis-side of a diphytanoyl PC membrane, macroscopic channel current was induced only at cis positive voltages. The single-channel recordings showed several cond...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Okazaki, Takashi, Sakoh, Machiko, Nagaoka, Yasuo, Asami, Koji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303083/
https://ncbi.nlm.nih.gov/pubmed/12829482
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