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Modifications of alamethicin ion channels by substitution of Glu-7 for Gln-7.

To evaluate the role of charged residues facing a pore lumen in stability of channel structure and ion permeation, we studied electrical properties of ion channels formed by synthesized native alamethicins (Rf50 (alm-Q7Q18) and Rf30 (alm-Q7E18)) and their analogs with Glu-7 (alm-E7Q18 and alm-E7E18)...

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Sonraí Bibleagrafaíochta
Main Authors: Asami, Koji, Okazaki, Takashi, Nagai, Yasuaki, Nagaoka, Yasuo
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302141/
https://ncbi.nlm.nih.gov/pubmed/12080114
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