Stability and Cu(II) Binding of Prion Protein Variants Related to Inherited Human Prion Diseases

All inherited forms of human prion diseases are linked with mutations in the prion protein (PrP) gene. Here we have investigated the stability and Cu(II) binding properties of three recombinant variants of murine full-length PrP(23–231)-containing destabilizing point mutations that are associated wi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cereghetti, Grazia M., Schweiger, Arthur, Glockshuber, Rudi, Van Doorslaer, Sabine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2003
Pynciau:
Spectroscopy, Imaging, Other Techniques
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302768/
https://ncbi.nlm.nih.gov/pubmed/12609901
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg