Ising Model of Cardiac Thin Filament Activation with Nearest-Neighbor Cooperative Interactions

We have developed a model of cardiac thin filament activation using an Ising model approach from equilibrium statistical physics. This model explicitly represents nearest-neighbor interactions between 26 troponin/tropomyosin units along a one-dimensional array that represents the cardiac thin filame...

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Hauptverfasser: Rice, John Jeremy, Stolovitzky, Gustavo, Tu, Yuhai, de Tombe, Pieter P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2003
Schlagworte:
Biophysical Theory and Modeling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302668/
https://ncbi.nlm.nih.gov/pubmed/12547772
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