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Excitation-Contraction Coupling Gain and Cooperativity of the Cardiac Ryanodine Receptor: A Modeling Approach

During calcium-induced calcium-release, the ryanodine receptor (RyR) opens and releases large amounts of calcium from the sarcoplasmic reticulum into the cytoplasm of the myocyte. Recent experiments have suggested that cooperativity between the four monomers comprising the RyR plays an important rol...

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Detalhes bibliográficos
Main Authors: Wang, Kai, Tu, Yuhai, Rappel, Wouter-Jan, Levine, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366799/
https://ncbi.nlm.nih.gov/pubmed/16126827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.058958
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