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Excitation-Contraction Coupling Gain and Cooperativity of the Cardiac Ryanodine Receptor: A Modeling Approach

During calcium-induced calcium-release, the ryanodine receptor (RyR) opens and releases large amounts of calcium from the sarcoplasmic reticulum into the cytoplasm of the myocyte. Recent experiments have suggested that cooperativity between the four monomers comprising the RyR plays an important rol...

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Detalles Bibliográficos
Main Authors: Wang, Kai, Tu, Yuhai, Rappel, Wouter-Jan, Levine, Herbert
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366799/
https://ncbi.nlm.nih.gov/pubmed/16126827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.058958
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