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Statistical Mechanics of Sequence-Dependent Circular DNA and Its Application For DNA Cyclization

DNA cyclization is potentially the most powerful approach for systematic quantitation of sequence-dependent DNA bending and flexibility. We extend the statistical mechanics of the homogeneous DNA circle to a model that considers discrete basepairs, thus allowing for inhomogeneity, and apply the mode...

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Bibliographic Details
Main Authors: Zhang, Yongli, Crothers, Donald M.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302599/
https://ncbi.nlm.nih.gov/pubmed/12524271
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