Cysteines beta93 and beta112 as probes of conformational and functional events at the human hemoglobin subunit interfaces.

Three variants of tetrameric human hemoglobin, with changes at the alpha1beta2/alpha2beta1-interface, at the alpha1beta1/alpha2beta2-interface, and at both interfaces, have been constructed. At alpha1beta2/alpha2beta1-interface the beta93 cysteine was replaced by alanine (betaC93A), and at the alpha...

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Detalhes bibliográficos
Main Authors: Vásquez, G B, Karavitis, M, Ji, X, Pechik, I, Brinigar, W S, Gilliland, G L, Fronticelli, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302502/
https://ncbi.nlm.nih.gov/pubmed/9876125
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