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Role of subunit interfaces in the allosteric mechanism of hemoglobin.

We calculate the surface area buried in subunit interfaces of human deoxyhemoglobin and of horse methemoglobin. A larger surface area is buried in deoxy- than in methemoglobin as a result of tertiary and quaternary structure changes. In both molecules the dimer-dimer interface is closepacked. This i...

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Detalhes bibliográficos
Main Authors: Chothia, C, Wodak, S, Janin, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431212/
https://ncbi.nlm.nih.gov/pubmed/1069263
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