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Validity of Gō models: comparison with a solvent-shielded empirical energy decomposition.

Do Gō-type model potentials provide a valid approach for studying protein folding? They have been widely used for this purpose because of their simplicity and the speed of simulations based on their use. The essential assumption in such models is that only contact interactions existing in the native...

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Bibliographic Details
Main Authors: Paci, Emanuele, Vendruscolo, Michele, Karplus, Martin
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302383/
https://ncbi.nlm.nih.gov/pubmed/12496075
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