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Self-consistent determination of the transition state for protein folding: Application to a fibronectin type III domain
We present a general approach in which theory and experiments are combined in an iterative manner to provide a detailed description of the transition state ensemble (TSE) for folding. The method is illustrated by applying it to TNfn3, a fibronectin type III domain protein. In the first iteration, a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141005/ https://ncbi.nlm.nih.gov/pubmed/12515856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232704999 |
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