Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency.

Cationic lipids are widely used for gene transfection, but their mechanism of action is still poorly understood. To improve this knowledge, a structure-function study was carried out with two pyridinium-based lipid analogs with identical headgroups but differing in alkyl chain (un)saturation, i.e.,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zuhorn, Inge S, Oberle, Volker, Visser, Willy H, Engberts, Jan B F N, Bakowsky, Udo, Polushkin, Evgeny, Hoekstra, Dick
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2002
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302298/
https://ncbi.nlm.nih.gov/pubmed/12324427
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