Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance.

We report constraints on the supramolecular structure of amyloid fibrils formed by the 40-residue beta-amyloid peptide associated with Alzheimer's disease (A beta(1-40)) obtained from solid-state nuclear magnetic resonance (NMR) measurements of intermolecular dipole-dipole couplings between (13...

Full description

Saved in:
Bibliographic Details
Main Authors: Balbach, John J, Petkova, Aneta T, Oyler, Nathan A, Antzutkin, Oleg N, Gordon, David J, Meredith, Stephen C, Tycko, Robert
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302222/
https://ncbi.nlm.nih.gov/pubmed/12124300
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items