The effect of core destabilization on the mechanical resistance of I27.

It is still unclear whether mechanical unfolding probes the same pathways as chemical denaturation. To address this point, we have constructed a concatamer of five mutant I27 domains (denoted (I27)(5)*) and used it for mechanical unfolding studies. This protein consists of four copies of the mutant...

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Main Authors: Brockwell, David J, Beddard, Godfrey S, Clarkson, John, Zinober, Rebecca C, Blake, Anthony W, Trinick, John, Olmsted, Peter D, Smith, D Alastair, Radford, Sheena E
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302160/
https://ncbi.nlm.nih.gov/pubmed/12080133
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