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The effect of core destabilization on the mechanical resistance of I27.

It is still unclear whether mechanical unfolding probes the same pathways as chemical denaturation. To address this point, we have constructed a concatamer of five mutant I27 domains (denoted (I27)(5)*) and used it for mechanical unfolding studies. This protein consists of four copies of the mutant...

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Détails bibliographiques
Auteurs principaux: Brockwell, David J, Beddard, Godfrey S, Clarkson, John, Zinober, Rebecca C, Blake, Anthony W, Trinick, John, Olmsted, Peter D, Smith, D Alastair, Radford, Sheena E
Format: Artigo
Langue:Inglês
Publié: 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302160/
https://ncbi.nlm.nih.gov/pubmed/12080133
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