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Mechanical Resistance of Proteins Explained Using Simple Molecular Models

Recent experiments have demonstrated that proteins unfold when two atoms are mechanically pulled apart, and that this process is different to when heated or when a chemical denaturant is added to the solution. Experiments have also shown that the response of proteins to external forces is very diver...

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Bibliographic Details
Main Authors: West, Daniel K., Brockwell, David J., Olmsted, Peter D., Radford, Sheena E., Paci, Emanuele
Format: Artigo
Language:Inglês
Published: Biophysical Society 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367027/
https://ncbi.nlm.nih.gov/pubmed/16214858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.071035
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