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Tropomyosin requires an intact N-terminal coiled coil to interact with tropomodulin.

Tropomodulins (Tmods) are tropomyosin (TM) binding proteins that bind to the pointed end of actin filaments and modulate thin filament dynamics. They bind to the N termini of both "long" TMs (with the N terminus encoded by exon 1a of the alpha-TM gene) and "short" nonmuscle TMs (...

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Bibliographic Details
Main Authors: Greenfield, Norma J, Fowler, Velia M
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302047/
https://ncbi.nlm.nih.gov/pubmed/11964245
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