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Structure and Tropomyosin Binding Properties of the N-Terminal Capping Domain of Tropomodulin 1

Two families of actin regulatory proteins are the tropomodulins and tropomyosins. Tropomodulin binds to tropomyosin (TM) and to the pointed end of actin filaments and “caps” the pointed end (i.e., inhibits its polymerization and depolymerization). Tropomodulin 1 has two distinct actin-capping region...

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Autores principales: Greenfield, Norma J., Kostyukova, Alla S., Hitchcock-DeGregori, Sarah E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305014/
https://ncbi.nlm.nih.gov/pubmed/15475586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051128
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