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Structure and Tropomyosin Binding Properties of the N-Terminal Capping Domain of Tropomodulin 1

Two families of actin regulatory proteins are the tropomodulins and tropomyosins. Tropomodulin binds to tropomyosin (TM) and to the pointed end of actin filaments and “caps” the pointed end (i.e., inhibits its polymerization and depolymerization). Tropomodulin 1 has two distinct actin-capping region...

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Main Authors: Greenfield, Norma J., Kostyukova, Alla S., Hitchcock-DeGregori, Sarah E.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305014/
https://ncbi.nlm.nih.gov/pubmed/15475586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051128
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