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Block of the ryanodine receptor channel by neomycin is relieved at high holding potentials.

In this study we have investigated the actions of the aminoglycoside antibiotic neomycin on K+ conductance in the purified sheep cardiac sarcoplasmic reticulum (SR) calcium-release channel (RyR). Neomycin induces a concentration- and voltage-dependent partial block from both the cytosolic and lumina...

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Bibliografske podrobnosti
Main Authors: Mead, Fiona, Williams, Alan J
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301991/
https://ncbi.nlm.nih.gov/pubmed/11916853
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