Tyrosine sulfation enhances but is not required for PSGL-1 rolling adhesion on P-selectin.

P-selectin glycoprotein ligand-1 (PSGL-1) is a large (240 kDa) glycoprotein found on the surface of nearly all leukocytes. The mature molecule is decorated with multiple N- and O-linked glycans and displays copies of the tetrasaccharide sialyl-Lewis(x) (sLe(X)), as well as a cluster of three tyrosin...

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Bibliographic Details
Main Authors: Rodgers, S D, Camphausen, R T, Hammer, D A
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301674/
https://ncbi.nlm.nih.gov/pubmed/11566773
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