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Modification of voltage-dependent gating of potassium channels by free form of tryptophan side chain.
Indole constitutes a major component of the side chain of the amino acid tryptophan. Application of indole slows activation of voltage-dependent potassium channels and reduces steady-state conductance in a voltage- and concentration-dependent manner. The steep concentration dependence indicates that...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1301495/ https://ncbi.nlm.nih.gov/pubmed/11423398 |
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