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Modification of voltage-dependent gating of potassium channels by free form of tryptophan side chain.

Indole constitutes a major component of the side chain of the amino acid tryptophan. Application of indole slows activation of voltage-dependent potassium channels and reduces steady-state conductance in a voltage- and concentration-dependent manner. The steep concentration dependence indicates that...

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Detalles Bibliográficos
Main Authors: Avdonin, V, Hoshi, T
Formato: Artigo
Idioma:Inglês
Publicado: 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301495/
https://ncbi.nlm.nih.gov/pubmed/11423398
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