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A single residue differentiates between human cardiac and skeletal muscle Na+ channel slow inactivation.

Slow inactivation determines the availability of voltage-gated sodium channels during prolonged depolarization. Slow inactivation in hNa(V)1.4 channels occurs with a higher probability than hNa(V)1.5 sodium channels; however, the precise molecular mechanism for this difference remains unclear. Using...

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Bibliografiske detaljer
Main Authors: Vilin, Y Y, Fujimoto, E, Ruben, P C
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301414/
https://ncbi.nlm.nih.gov/pubmed/11325725
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