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Extensibility of isoforms of cardiac titin: variation in contour length of molecular subsegments provides a basis for cellular passive stiffness diversity.

Titin is a giant polypeptide that spans between the Z- and M-lines of the cardiac muscle sarcomere and that develops force when extended. This force arises from titin's extensible I-band region, which consists mainly of three segment types: serially linked immunoglobulin-like domains (Ig segmen...

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Detalles Bibliográficos
Main Authors: Trombitás, K, Redkar, A, Centner, T, Wu, Y, Labeit, S, Granzier, H
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301197/
https://ncbi.nlm.nih.gov/pubmed/11106626
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